Influences of strict heart rate management on heart function and quality of life in patients with chronic heart failure
WANG Lu
DONG Meng-qing
WU Di
GE Zhi-ru
Abstract：Objective To compare the influences of strict management of resting heart rate (HR) and routine treatment on heart function and quality of life in patients with chronic heart failure (CHF). Methods CHF patients (n=93) were randomly divided into test group (strict control of HR, n=48) and control group (routine treatment, n=45), and all given heart failure guideline directed therapy. The test group was given strict control of resting HR for target HR through adjusting the dose of metoprolol sustained-release tablets. After follow-up for 1 y, New York Heart Function Assessment (NYHA), left ventricular ejection fraction (LVEF), left ventricular end-diastolic inner diameter (LVEDd), left ventricular end systolic diameter (LVESd), plasma NT-proBNP, 6-minute walk test (6MWT) and scores of Minnesota Table of Quality of Life were compared between 2 groups. Results The difference in LVEF,LVEDD,NYHA, plasma NT-proBNP and 6MWT had statistical significance compared between 2 groups (P<0.05) after strict HR control. Conclusion Strict management of resting HR can improve heart function and quality of life in CHF patients.
Keywords：Resting heart rate controlChronic heart failureHeart functionMetoprolol sustained-release tabletsQuality of life
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 35-37 )