Correlation between periodontal disease and hypertension risk:a Meta-analysis based on observational studies
WENG Hong
YAN Jin-zhu
TIAN Guo-xiang
LENG Wei-dong
XIA Ling-yun
ZENG Xian-tao
Abstract：Objective To review the relationship between periodontal disease and hypertension risk by applying Meta-analysis. Methods The databases of PubMed, EMbase, CBM, CNKI and WanFang Database were retrieved for collecting the observational studies about the relationship between periodontal disease and hypertension risk from database establishing time to Mar. 2014. All studies were screened, extracted and reviewed according to NOS tool by 2 researchers, and then given a Meta-analysis by using CMA v2.2 software. Results There were finally 7 case-control studies and 3 cohort studies included. The results of Meta-analysis showed that periodontal disease improved the incidence of hypertension by 1.86 times (OR=1.86, 95%CI:1.32-2.62, P<0.01), and sensitivity analysis showed that the results were stable. The subgroup analysis showed that cohort studies and American people were not significant. Publication bias was mild. Conclusion Periodontal disease might be a significant risk factor to hypertension based on current evidence. Due to the limitation of this Meta-analysis, the results should be confirmed in the future.
Keywords：Periodontal diseaseHypertensionMeta-analysisRisk factors
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 16-19 )