Clinical significance of brain natriuretic peptide and troponin T levels in reviewing severity of acute pulmonary embolism
ZHOU Xiao-feng
LIU Qing-yu
CHEN Hong-li
LIU Dan
WANG Jie
ZHAO Lin
Abstract:Objective To discuss the clinical significance of brain natriuretic peptide (BNP) and troponin T (TnT) levels in reviewing severity of acute pulmonary embolism (APE).Methods APE patients (n=74, male 42 and female 32) aged from 19 to 84 (average age=55.1±16.6) were chosen from Dec. 2010 to Feb. 2014, and divided into 3 groups according to the levels of BNP and TnT, including group A (negative BNP+TnT,n=40), group B (negative BNP only,n=24) and group C (positive BNP+TnT,n=10). The levels of BNP and TnT were detected in all patients, and symptom relieving time after admission and the total hospitalization time were recorded.Results Compared with group A, the percentage of faint patients increased in group B (2.5%vs. 16.7%), and compared with group B, that increased in group C (16.7%vs. 50.0%, allP<0.05). Compared with group B, BNP level increased in group C (P<0.05). TnT was positively correlated to the total hospitalization time (r=0.537,P<0.05).Conclusion BNP and TnT are important indexes for reviewing severity of APE. If patients have both increased BNP and TnT, they should be treated actively.
Keywords:Acute pulmonary embolismBrain natriuretic peptideTroponin TFaintTime of symptom relievingTotal hospitalization time
Publication Date:2014-01-01
Online Publishing Date:2025-08-15(First online date of this platform, not the publication date of the document)
Pages:3( 736-738 )
