Influencing factors of brachial-ankle pulse wave velocity in healthy check-up receivers
GUO Yue-ling
ZHANG Hai-ying
MA Chun-mei
HAN Shu-qin
Abstract：Objective To analyze the influencing factors of brachial-ankle pulse wave velocity (baPWV) in healthy check-up receivers.Methods The healthy check-up receivers (n=1579) were chosen from Mar. 2011 to Mar. 2012, and their levels of total cholesterol (TC), triglyceride (TG), low-density lipoprotein-cholesterol (LDL-C), high-density lipoprotein-cholesterol (HDL-C), fasting plasma glucose (FPG), body mass index (BMI), systolic blood pressure (SBP) and diastolic blood pressure (DBP) were detected. The level of bilateral limb baPWV was detected by using atherosclerosis tester and baPWV≥14 m/s was defined as elevated arterial stiffness. The influencing factors of arterial elasticity were determined by applying multiple Logistic regression analysis, and predictive value of related influencing factors to baPWV was estimated by using ROC curve.Results There was significant difference in BMI, TG, TC, LDL-C, SBP, DBP, FPG and age between normal group and elevating group (allP<0.01). The multiple Logistic regression analysis showed that age, SBP, TG and BMI were independent influencing factors of baPWV (allP<0.01). ROC curve analysis showed that the area under AUC curve of SBP was the largest (0.81), and SBP sensitivity was 64% and its specificity was 81% when cut-off point of SBP was selected at 135 mmHg.Conclusion Age, SBP, TG and BMI are independent influencing factors of baPWV, and SBP is the most important predictive factor.
Keywords：Brachial-ankle pulse wave velocityHealthy check-upInfluencing factors
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 711-713 )