Clinical characteristics of initial acute myocardial infarction in young patients

ZHANG Qian; FU Qiang; ZHONG Jian; WEI Peng; ZHU Ke; LU Yi

doi:10.3969/j.1674-4055.2014.05.21

Abstract：Objective To discuss the clinical characteristics of initial acute myocardial infarction (AMI) in young patients. Methods The young patients (n=42) with initial ST-segment elevation myocardial infarction (STEMI) were chosen as young group from Jun. 2011 to Oct. 2013, 52 elderly patients with STEMI were chosen as elderly group, and other 20 cases without CHD after CTA were chosen as control group during the same period. The general data, outcomes of CAG, and admission and discharge GRACE integrals were collected. The difference in high-sensitivity C-reactive protein (hs-CRP), blood fat, BNP, Gensini integral, and admission GRACE integral were analyzed between young group and elderly group or control group. Results There were 42.9%patients with indicators in young group and 15.4%in elderly group (P<0.05). In young group, most patients were male and the percentage of those with smoking history, drinking history and CHD family history were higher than those in elderly group (P<0.05), chest pain and other symptoms were typical, and lesion vessels of coronary artery were less than those in elderly group (P<0.05). The correlation analysis showed that admission GRACE integral was negatively correlated to hs-CRP, Gensini integral and HDL-C (P<0.01), and positively correlated to BNP (P<0.01). The discharge GRACE integral was negatively correlated to hs-CRP and Gensini integral (P<0.01), and positively correlated to BNP and age (P<0.01). Conclusion The young patients with initial AMI are mainly male and have family history, indicators and multiple high-risk factors. The outcomes of CAG show the coronary lesion are mostly single vessel lesion, and early monitoring and intervention may improve prognosis.