Factors related to exercise capacity in patients with hypertension accompanied by chest pain
TIAN Ting
ZHAO Sheng
ZHAO Xi-zhe
MA Feng-yun
LUO Wei
WANG Feng
SUN Shu-hong
Abstract：Objective To discuss the influence factors related to exercise capacity in patients with hypertension accompanied by chest pain during treadmill exercise test. Methods The patients (n=136) with hypertension accompanied by chest pain were chosen and given symptom-limited treadmill exercise test. All patients were divided into group I (achieved exercise capacity≥predicted exercise capacity) and group II (achieved exercise capacity<predicted exercise capacity). The indexes of age, sex, body mass index (BMI), blood fat, fasting plasma glucose (FPG), fasting insulin (FINS) and homeostasis model assessment of insulin resistance (HOMA-IR) were compared between 2 groups. The influence factors related to exercise capacity were analyzed by using multiple linear regression analysis (MLR). Results In group II, resting heart rate (RHR), BMI, FINS and HOMA-IR were significantly higher than those in group I [(78.3±5.4) time/min vs. (72.1±6.0) time/min, P<0.001], [(26.4 ±2.8) kg/m2 vs. (24.1±2.6) kg/m2, P<0.001], [(12.9±4.8)μIU/ml vs. (8.6±2.6)μIU/ml, P<0.001] and [(3.82± 1.66) vs. (2.21±1.23), P<0.001]. MLR showed that sex (female), age, RHR, HOMA-IR were negatively correlated to exercise capacity (standard regression coefficientβwas, respectively,-0.547,-0.396,-0.336 and-0.438, all P<0.05). Conclusion In the patients with hypertension accompanied by chest pain, female, aging, RHR increasing and higher HOMA-IR are influence factors reducing exercise capacity.
Keywords：HypertensionExercise capacityInsulin resistanceResting heart rate
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 458-460,463 )