Predictive value of B-type natriuretic peptide to atrial fibrillation in patients with heart failure
HU Feng-chao
WANG Pei
YANG Rui
Abstract：Objective To investigate the predictive value of B-type natriuretic peptide (BNP) to atrial fibrillation (AF) in patients with heart failure through detecting the level of serum BNP level. Methods The patients (n=169) were chosen from Jul. 2010 to Dec. 2013 and among them, 17 were missed and 152 were followed up. There were 79 male patients and 73 female ones aged from 37 to 71, and average age was (48±11) years old. All patients were divided, according to follow-up results, into AF group (n=29) and sinus rhythm group (n=123). All patients were given Holter test before chosen and after followed up for 1 y, and at the same time BNP level was detected. Results After 1 y, 152 patients completed follow-up and AF was recorded in 29 patients. BNP level was significantly higher in AF group [(312.21±52.78) pg/mL] than that in sinus rhythm group [(218.24±67.45) pg/mL, P<0.01]. The results of multi-factor analysis showed that age (OR=4.162, 95%CI:1.521-7.132) and LVEF (OR=1.027, 95%CI:0.939-1.058) were independent risk factors of heart failure complicating AF. Conclusion The level of serum BNP is important to the prediction of AF in patients with heart failure.
Keywords：B-type natriuretic peptideAtrial fibrillationHeart failurePredictive value
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：2( 430-431 )