Influences of diabetes and dialysate protein loss on cardiac structure in patients with peritoneal dialysis
WAN Mei-yan
ZHANG Shu-jian
CUI Yong-jun
SUI Xiao-ni
YU Long-li
ZOU Zuo-jun
Abstract：Objective To investigate the influences of diabetes and dialysate protein loss on cardiac structure and heart function in patients treated with peritoneal dialysis (PD). Methods The patients (n=68) treated with PD for 12 m were chosen, and among them 32 with and 36 without diabetes (diabetes group and non-diabetes group). The biochemical indexes and 24-h dialysate protein quantity were detected in 2 groups before and after PD. The changes of LAD, LVD, IVST, LVPWT and LVEF were detected and compared by using color Doppler ultrasound before and after PD. Results All indexes had no statistical difference in 2 groups before PD. After PD for 1 y, there was difference in serum albumin, dialysate protein loss, IVST, LVPWT and LVEF between 2 groups (P<0.05). The correlation analysis showed that dialysate protein loss was negatively correlated to serum albumin and LVEF (r=-0.476, P<0.01;r=-0.269, P<0.05), and positively correlated to IVST and LVPWT (r=0.461, P<0.01;r=0.346, P<0.01). Conclusion Dialysate protein loss will increase in diabetic patients after PD, which can further influence patient’s cardiac structure and heart function.
Keywords：Peritoneal dialysisProteinLossCardiac structure and function
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 416-418 )