A Meta-analysis on curative effect of Shengmai Injection on dilated cardiomyopathy
LI Jin
TANG Qi-zhu
ZHANG Wen-bin
XIANG Shi-zhao
HU Zhe-fu
Abstract：Objective To review the curative effect of Shengmai Injection on dilated cardiomyopathy (DCM). Methods The databases of Cochrane Library, PubMed, EMbase, Goolge Scholar, CNKI, WangFang Database, VIP Database and CBMdisc were retrieved with computer for searching the randomized controlled trials (RCT) about treatment of DCM with routine therapies combining Shengmai Injection (treatment group) and with routine therapies only (control group) published from database establishing time to Dec. 2013 supplemented manually for searching reference. After screening literature, data extracting and quality reviewing according to inclusion and exclusion criteria, the data was given a Meta-analysis by using RevMan5.2 software. Results There were totally 8 RCT included involving 481 patients. The results of Meta-analysis showed that the curative effect was better in treatment group than that in control group (OR=4.24, 95%CI:2.46-7.30, P<0.00001), and LVEF was improved in treatment group (MD=7.69, 95%CI:1.84-13.55, P=0.01). Conclusion The routine therapies combining Shengmai Injection has an improve curative effect on DCM, while more large-sample and multiple-center RCT with rigorous design are required for further identifying this tendency because of limited quantity and quality of this study.
Keywords：Shengmai InjectionDilated cardiomyopathyMeta-analysis
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 382-385 )