Features of heart rate variability in patients with coronary heart disease
SHEN Yan-fang
JIANG Xue-jun
LEI Yu-hua
HUANG Hao
Abstract：Objective To understand the features of heart rate variability (HRV) in the patients with coronary heart disease (CHD). Methods CHD patients (CHD group, n=156) and normal medical examiners (control group, n=128) were chosen and given 24-h ambulatory blood pressure monitoring (ABPM). CHD group was given color Doppler ultrasonic imaging apparatus for measuring left ventricular ejection fraction (LVEF) and then divided into normal LVEF group (LVEF≥50%) and lower LVEF group (LVEF<50%), and meanwhile CHD group was divided into groups according to age. The parameters of HRV were calculated including SDNN, SDANN, RMSSD, pNN50, TP, LF and HF, and the features of these parameters were compared and analyzed among all groups. Results SDNN (96.2±28.8 ms vs. 138.1±27.7 ms), SDANN (79.4±27.1 ms vs. 130.4±28.2 ms), RMSSD (24.3 ms±9.8 vs. 31.2 ±9.3 ms), pNN50 (8.5±3.2 ms vs. 12.3±3.9 ms) and HF (233.6±95.5 ms2 vs. 292.3±100.2 ms2) all decreased significantly in CHD group compared with control group (all P<0.05). SDNN, SDANN, RMSSD, pNN50, TP and HF decreased in lower LVEF group compared with normal LVEF group (all P<0.05), while the comparison in SDNN, TP, RMSSD, pNN50, LF and HF showed no statistical difference among different age groups (P>0.05). SDANN was higher in 35-45 year-old group than that in 55-65 year-old group (P<0.05). Conclusion In CHD patients, HRV decreases, and the decrease of LVEF will further exacerbate the damage of autonomic nervous function.
Keywords：Heart rate variabilityCoronary heart diseaseLeft ventricular ejection fraction
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 302-305 )