Clinical application of low kilovolt technique combining low concentration of contrast medium in coronary CT angiography
HU Gang
HAN Wei
LU Jun-liang
CHEN Hua
LIU Geng-huai
ZHANG Zhi-gang
ZHOU Yan
FENG Meng
WANG Li
LI Hong-min
WANG Li-wei
WU Xin-huai
Abstract：Objective To discuss the feasibility of low kilovolt (100 kV) technique combining low concentration of contrast medium in coronary CT angiography (CCTA). Methods The patients (n=80, BMI≤26) with planed CCTA were chosen and randomly divided into group A and group (each n=40). Group A was given low-kV (100 kV) CCTA with Visipaque (270 mg/mL) and self-adaptive iterative reconstruction algorithm (ASiR), and group B, routine kV (120 kV) CCTA with Omnipaque (350 mg/mL) and filter back-projection algorithm (FBP). The CT values and SD values of aorta, subcutaneous fat and erector spine muscle were measured, and mean SD value was calculated as image noise. The CT values and SD values of left anterior descending artery (LAD), left circumflex (LCX) and right coronary artery (RCA) were measured, and contrast-to-noise ratio (CNR) was calculated. All images were given quality subjective scoring by using 5-score method. The CT dose index was recorded and effective radiation dose was calculated. Results The average iodine dosage decreased by 22.8%in group A compared with group B. The CT values, CNR values, image noise and image quality subjective scores of LAD, LCX and RCA had no statistical difference between 2 groups (all P>0.05). The effective radiation dose was significantly lower in group A than that in group B (P<0.05). Conclusion To the patients with BMI≤26, low concentration of contrast medium and low kilovolt CCTA can provide similar image quality, lower iodine dosage and lower effective radiation dose compared with conventional scanning.
Keywords：Computed tomographyX-ray computerCoronary arteryRadiation doseContrast medium
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 285-287 )