Application values of ankle-brachial index, toe-brachial index and LDL-C/HDL-C to coronary ;artery disease
GENG Song
SUN Yu-jiao
ZHANG Peng-xiang
LIU Jie-wu
QI Guo-xian
Abstract：Objective To investigate the application values of ankle-brachial index (ABI), toe-brachial index (TBI) and ratio of LDL-C to HDL-C (LDL-C/HDL-C) in patients with coronary artery disease. Methods The patients (n=160) were chosen from the Department of Cardiovascular Diseases of the First Affiliated Hospital of China Medical University from Oct. 2011 to Feb. 2013, and divided into control group (n=57, severity of CAS≤25%) and CAS group (n=103, severity of CAS>25%) according to the outcomes of CTA. CAS group was further divided into single-vessel group (with single coronary vessel lesion, n=30), double-vessel group (with lesion of 2 coronary vessels, n=31), 3-vessel group (with lesion of 3 coronary vessels, n=42), mild-lesion group (n=55, CAS≤50%) and mid-severe-lesion group (n=48, CAS>50%). All patients were given examinations on ABI, TBI and LDL-C/HDL-C, and the changes of ABI, TBI and LDL-C/HDL-C and their values to estimating the severity of coronary artery lesion were analyzed in all groups. Results ABI and TBI had a descent trend and LDL-C/HDL-C had a ascent trend in control group, single-vessel group, double-vessel group and 3-vessel group, and comparison in ABI, TBI and LDL-C/HDL-C showed statistical difference (P<0.05). The comparison in ABI, TBI and LDL-C/HDL-C showed statistical difference among 3-vessel group, control group and single-vessel group (P<0.05). The comparison in ABI showed statistical difference between double-vessel group and control group (P<0.05). ABI and TBI had a descent trend and LDL-C/HDL-C had a ascent trend in control group, mild-lesion group and mid-severe-lesion group, and comparison in ABI, TBI and LDL-C/HDL-C showed statistical difference (P<0.05). The comparison in ABI, TBI and LDL-C/HDL-C showed statistical difference between mid-severe-lesion group and control group (P<0.05). The comparison in ABI showed statistical difference between mid-severe-lesion group and mild-lesion group and between mild-lesion group and control group (P<0.05). Conclusion ABI can reflect well the severity of coronary artery lesion, and the lower the ABI value, the severer the CAS, which, however, can not fully reflect the range of coronary artery lesion. ABI, TBI and LDL-C/HDL-C have some diagnosis values to coronary artery lesion but they are not suitable for reviewing the severity and range of coronary artery lesion.
Keywords：Coronary heart diseaseAnkle-brachial indexToe-brachial indexLow-density lipoprotein-cholesterolHigh-density lipoprotein-cholesterol
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 204-207 )