Influences of non-dipper hypertension complicating diabetes on circadian rhythm of blood pressure and ;target organ damage in male elderly patients
SUN Yu-qing
LUO Lei-ming
WANG Rui-ying
QIN Ai-mei
Abstract：Objective To investigate the influences of non-dipper hypertension complicating diabetes on circadian rhythm of blood pressure and target organ damage in male elderly patients. Methods The patients (n=656) were chosen and divided into diabetes group (n=366) and non-diabetes group (n=290) according to whether they had complicating diabetes or not. The changes of FBG, TC, TG, LDL-C, HDL-C, NT-proBNP and TnT were detected by using automatic biochemical analyzer, and eGFR was calculated according to MDRD formula. The patients were given cardiac ultrasound examinations for computing LVMI. The difference in all above indexes was analyzed in 2 groups. Results The difference in the levels of Hb [(132.3±15.62) mmol/L vs. (131.14±12.32) mmol/L], TG [(1.52 ±1.09) mmol/L vs. (1.35±0.69) mmol/L], HDL-C [(1.15±0.32) mmol/L vs. (1.20±0.33) mmol/L], T3 [(4.05±0.69) nmol/L vs. (4.27±0.85) nmol/L], TnT [(0.05±0.18)μg/L vs. (0.02±0.02)μg/L], LVMI [(179.82±44.83) g/m2 vs. (168.21±32.16) g/m2], 24-h SBP [(125.00±12.14) mmHg vs. (123.00±11.11) mmHg], daytime SBP [(127.00 ±13.09) mmHg vs. (125.30±12.29) mmHg], nighttime SBP [(128.12±16.28) mmHg vs. (125.34±14.59) mmHg], and ratio of daytime SBP to nighttime SBP [(0.99±0.05) mmHg vs. (0.98±0.04) mmHg] had statistical significance compared between 2 groups (all P<0.05). Conclusion The increase of SBP is more serious, disappearance of circadian rhythm is more obvious, and heart function damage is more exacerbated in male elderly patients with non-dipper hypertension complicating diabetes.
Keywords：Aged menNon-dipper hypertensionDiabetes
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 168-171 )