The differences of effectiveness and safety of radiofrequency catheter ablation in treatment of atrial fibrillationbetween different genders
TAN Chen
XU Wei
HU Xue-hong
LIU Jian-guo
SHI Hong-ling
CHEN Nian
LU Min
CUI Jun-yu
LI Jun-xia
Abstract：Objective To investigate the influences of gender on effectiveness and safety of radiofrequency catheter ablation (RFCA) in treatment of atrial fibrillation.Methods The patients (n=116) were chosen from Mar. 2009 to Jan. 2013, and divided into male group (n=71) and female group (n=45). All patients were followed up for (6-51) months, and recrudescence of atrial fibrillation was defined according to symptoms, ECG and Holter during the follow-up. The recrudescence patients were given RFCA once again, and the causes of recrudescence were identified. The success rate of RFCA and incidence of complications (including hematoma at puncture site, pericardial tamponade, cerebral embolism, cerebral hemorrhage, pulmonary vein stenosis and left atrial esophageal fistula) were compared between two groups. The correlation between recurrent rate and clinical features (including age, BMI, LVEF, medical history and complications) was analyzed.Results The success rate of first RFCA was significantly higher in male group than that in female group (83.1%vs. 66.67%,P=0.046). The average age was higher in female group than that in male group. There was no statistical difference in complications between two groups. Logistic regression analysis showed that the recurrent rate was higher in female group (OR=3.3,P=0.049). The cause of recrudescence was mainly non-PV triggers, and furthermore it was related to diabetes in male group (OR=1.99,P=0.037).Conclusion The time of RFCA is later and the success rate of single RFCA is lower in female patients with atrial fibrillation, while there is no difference in safety between female patients and male ones.
Keywords：Atrial fibrillationCircumferential pulmonary vein isolationRadiofrequency catheter ablationGender
Publication Date：2013-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 627-629 )