Influence of depression on heart rate turbulence in patients with angina coronary heart disease
ZHENG Ju
YOU Hua
WU-Yan-ming
Abstract：Objective To investigate the influence of depression on heart rate turbulence (HRT) in the patients with angina coronary heart disease (CHD).Methods The patients (n=78) were chosen from Wujiang First People’s Hospital of Suzhou City from Jan. 2008 to Feb. 2012, and their depression status was assessed by using Zung Self-rating Depression Scale (SDS). The patients (n=40) without depression (SDS scores<50) were included into control group and those (n=38) with depression were included into observation group. The observation group was further divided into mild group (50≤SDS scores<60,n=14), moderate group (60≤SDS scores<70, n=14) and severe group (SDS scores≥70,n=10) according to SDS scores. All patients were given examinations of ambulatory electrocardiogram (ECG), and detection of sinus heart rate turbulence (HRT) parameters including heart rate turbulance onset (TO) and heart rate turbulence slope (TS) for comparing the difference between two groups. Results TO increased significantly [(2.16±1.06)%vs. (1.54±0.68)%,P=0.027] and TS decreased significantly [(2.33±1.95) ms/RRIvs. (4.47±3.89) ms/RRI,P=0.014] in observation group compared with control group. The analysis on sub-groups of observation group showed that TO increased gradually and TS decreased gradually as depression exacerbated.Conclusion Depression can attenuate HRT significantly, and HRT will more significant as depression exacerbates.
Keywords：AnginaDepressionSinus heart rate turbulenceAmbulatory electrocardiogram
Publication Date：2013-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：2( 602-603 )