Clinical significances of SVO2 and NT-proBNP after reperfusion therapy in patients with acute myocardial infarction
ZHAO Rui-ping
WANG Li-qing
Abstract：Objective To discuss the relationship between the levels of NT-proBNP and SVO2 and prognosis in the patients with acute myocardial infarction (AMI). Methods The patients (n=120) with first-attack AMI were chosen with reperfusion treatment (intravenous thrombolysis or emergency PCI) within 6 h after onset of chest pain from Central Hospital of Baotou City from Jul. 2011 to Jul. 2012. The levels of NT-proBNP and SVO2 were detected and then according to the detecting outcomes, the patients were divided into group A (n=60, SVO2>60%, NT-proBNP<1000 pg/mL) and group B (n=60, SVO2<60%, NT-proBNP>1000 pg/mL). The changes of LVEF, and incidence of major adverse cardiovascular events within 6 months (MACE, including sudden cardiac death, cardiogenic shock, malignant arrhythmia and heart failure) were compared between two groups. The correlation between NT-proBNP and SVO2 and MACE was given Person analysis. Results After treatment, LVEF was higher in group A than that in group B (54.75%±5.18%vs. 34.65%±8.11%), and the incidence of MACE was significantly lower in group A than that in group B (10.0%vs. 16.7%, P<0.05). Person analysis showed that NT-proBNP level was positively correlated to MACE incidence (r=0.474, P<0.01) and SVO2 was negatively correlated to MACE incidence (r=-0.834, P<0.01). Conclusion The heart function recovered well in AMI patients (with NT-BNP<1000 pg/mL and SVO2>60%) after treatment, prognosis is good, and the levels of NT-proBNP and SVO2 are correlated to heart function.
Keywords：SVO2NT-proBNPAcute myocardial infarctionReperfusion therapyClinical significance
Publication Date：2013-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 485-486,539 )