Treatment of non-ischemic cardiomyopathy in 18 patients
ZHU Shu-shu
LU Xiang
Abstract：Objective To study the relationship among serum biomarkers, accessory examination indexes and adverse events in the patients with non-ischemic cardiomyopathy (NICM). Methods The NICM patients (n=18) were chosen from the Second Affiliated Hospital of Nanjing Medical University from Jan. 2004 to Oct. 2011, and among them 4 died in hospital (death group) and other 14 survived (survival group). The levels of type B natriuretic peptide (BNP), cardiac actin (cTnI) and myoglobin (MYO) were detected by using ELISA. Meanwhile the indexes of NYHA grading, heart rate (HR), mean arterial pressure (MAP), LVEF and cardiothoracic ratio (CTR) were compared between two groups during hospitalization. Results Compared with survival group, MAP was significantly lower, [(78 ±15) mmHg vs. (87±15) mmHg, P<0.05], LVEF decreased [(28.3±7.2)%vs. (32.2±7.4)%, P<0.05] and BNP increased significantly [(2231±556) pg/ml vs. (647±231) pg/ml, P<0.05]. Conclusion Increased BNP, significantly decreased LVEF and slightly increased cTnI can indicate the higher risk of adverse events in NICM patients.
Keywords：Non-ischemic cardiomyopathyType B natriuretic peptideCardiac magnetic resonance imaging
Publication Date：2013-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：2( 479-480 )