Meta-analysis on curative effect of Huangqi Injection on adult viral myocarditis
ZHOU Meng-jiao
TANG Qi-zhu
Abstract：Objective To review the curative effect of Huangqi Injection on adult viral myocarditis. Methods The databases of PubMed, MEDLINE, CCTR, CNKI (1994-2013), Wanfang (1999-2013) and VIP (1989-2013) were retrieved for collecting the randomized controlled trials (RCTs) on the comparison of treating adult viral myocarditis with routine Western medical therapy combining Huangqi Injection (experimental group) or routine Western medical therapy (control group). The eligible RCTs were given Meta-analysis. Results There were totally 14 eligible RCTs included and the quality of all RCTs reached grade B. The results of Meta-analysis showed that the curative effect was better in experimental group than that in control group and the total effective rate was Z=8.91 (P<0.001, OR=4.55, 95%CI:3.26-6.35). When the treatment ended, the changes of ECG ST-T segment and effective rate of premature beat had statistical difference (changes of ECG ST-T segment:OR=5.82, 95%CI:3.40-9.96;decrease of premature beat:OR=4.88, 95%CI:2.83-8.41). The analysis results of funnel plots showed that there was barely bias in the Meta-analysis on curative effect and ECG changes. Conclusion Routine Western medical therapy combining Huangqi Injection can significantly improve curative effect and relief the symptoms in the patients with adult viral myocarditis.
Keywords：Huangqi InjectionViral myocarditisAdultMeta-analysis
Publication Date：2013-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 449-452 )