Clinical observation on treatment of angina pectoris with Yixinshu Capsules
ZHOU Jiang
GUO Jing-tao
WANG Qing-lei
WANG Fu-hua
DAI Yan-yan
SHI Xin
Abstract：Objective To observe the curative effect of Yixinshu Capsules on angina pectoris (AP). Methods The patients (n=197) with AP were chosen from the Central Hospital of Chengde City from Jan. 2011 to Dec. 2011, and then randomly divided into control group (n=98) and treatment group (n=99). The control group was given isosorbide dinitrate tablets (Xioaxintong, 10 mg/tid) and treatment group was additionally given Yixinshu Capsules (3 capsules/tid) for two months. The attack of AP and changes of blood pressure, heart rate and electrocardiogram (ECG) were observed before and after treatment. The occurrence of adverse events (including headache, dizziness and changes of whole body skin) was recorded during treatment. The standard of curative effect was set as AP symptoms disappeared, attack frequency of AP reduced by 50%and AP grades reduced over 1 grade or ST segment of ECG rose again equaled to or over 0.5 mV. Results The curative effect on AP was higher in treatment group than that in control group (95.96%vs. 73.47%, P<0.01). There were no statistical differences (P>0.05) in heart rate [(73.6± 6.2) times/min vs. (75.8±6.1) times/min] and blood pressure [SBP:(137.8±19.4) mmHg vs. (136.8±18.9) mmHg, DBP:(84.5±11.7) mmHg vs. (83.6±11.8) mmHg] between two groups. There were no adverse reactions observed. Conclusion Yixinshu Capsules can improve the curative effect on AP with higher safety.
Keywords：Coronary heart diseaseAngina pectorisYixinshu CapsulesIsosorbide dinitrate tablets
Publication Date：2013-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：2( 394-395 )