Correlation between high-normal of hypersensitive TSH and dyslipidemia
LI Jian-jun
RAO Xiao-pang
XU Mei-hua
Abstract：Objective To discuss the correlation between high-normal range of hypersensitive thyroid stimulating hormone (TSH) and dyslipidemia. Methods The health cases (n=156) with physical examination were chosen from the People’s Hospital of Chengyang District of Qingdao City from Jan. 2010 to Jan. 2011. The level of hypersensitive TSH was detected by using electro-chemiluminescence immunoassay and all cases were divided into low-normal range group (0.4 mIU/L<uTSH<2.9 mIU/L, n=70) and high-normal range group (3.0 mIU/L<uTSH<4.5 mIU/L, n=86). The indexes were detected in all cases including height, weight, waistline, hipline, blood pressure, blood fat, fasting blood glucose (FBG) and functions of liver and kidney. The difference in these indexes was compared between two groups and the relationship between hypersensitive TSH and blood fat was analyzed by applying multivariate linear regression. Results The level of total cholesterol (TC) was significantly higher in high-normal range group than that in low-normal range group [(6.54±1.71) mmol/L vs. (5.76±1.54) mmol/L, P<0.05], and meanwhile the incidence of hypercholesteremia was significantly higher in female cases (40.72%vs. 23.54%, P<0.01). After adjusting age, sex, BMI and FBG, the results of multivariate linear regression showed that there was a correlation between high-normal hypersensitive TSH and TC level. Conclusion High-normal hypersensitive TSH is an influencing factor on TC level, which is more significant in the female.
Keywords：DyslipidemiaHypersensitive thyroid stimulating hormoneHigh-normal range
Publication Date：2013-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 385-387 )