Advances in compression coating technology for sustained and controlled-release drug delivery systems
CHEN Xiu-yi
ZHANG Wen
CHEN Chao
FENG Jing
WANG Jin-hu
LI Zhao-ming
LI Da-wei
Abstract：In the past two decades,the technology of compression-coated tablets has developed and pro-gressed rapidly.Particularly,for the stepwise compression-coating technology,both the machine production capaci-ty and the tablets quality have been greatly improved.And because the application of new excipients and new phar-maceutical technology,the prescription design ideas have been much optimized.Zero-order release tablets,pulsa-tile drug delivery tablets,floating drug delivery tablets,and colonic drug delivery tablets can be produced by com-pression coating technology,which can make blood drug concentrations more stable,improve the bioavailability of drugs or reduce adverse drug reactions,so the treatment of some diseases can be improved by these drug delivery tablets.
Keywords：compression coatingsustained and controlled-releasezero-order releasepulsatile drug deliv-eryfloating drug deliverycolonic drug delivery
Publication Date：2026-04-30
Online Publishing Date：2026-08-14(First online date of this platform, not the publication date of the document)
Pages：8( 853-860 )