Research advances on iridoids of Eucommia ulmoides Oliv.
ZHANG Bao-jun
HONG Yan-long
ZHANG Lei
WANG Jian-ying
Abstract：Eucommia ulmoides Oliv.,as a traditional tonic medicinal material in China,has a long history of medicinal use and holds broad prospects for developing medicinal and food homologous products.The plant is rich in iridoids,which have garnered extensive attention and research in recent years due to their structural diversity and pharmacological versatility.To date,59 iridoid components have been isolated and identified from Eucommia ulmoides Oliv.,including 40 glycosides and 19 non-glycosides.Modern pharmacological studies have revealed that these iridoids,as one of the major active constituents,exhibit a wide range of biological effecte-such as neuroprotective,bone protective,renal-and hepatoprotective,anti-oxidant,anti-inflammatory,anti-tumor,analgesic,anti-atherosclerotic,and anti-hypertensive activities.However,the pharmacological roles of most iridoids from Eucommia ulmoides remain to be further investigated and systematically elucidated.This review summarizes the chemical structures,varieties and pharmacological effects of iridoids of Eucommia ulmoides Oliv.,aiming to provide a scientific basis for future studies on their pharmacological mechanisms and structure-activity relationships,as well as to establish a theoretical foundation for guiding the development of new drugs and drug-food homologous products.
Keywords：Eucommia ulmoides Oliv.iridoidschemical constituentspharmacological effects
Publication Date：2026-01-15
Online Publishing Date：2026-08-14(First online date of this platform, not the publication date of the document)
Pages：9( 46-54 )