Research progress and clinical application prospect of betel nut and its active components:pharmacological and toxicological effects
YUAN Shao-shuang
SUN Zheng-qing
ZHANG Zhao-hui
XU Qiang
Abstract：Modern research reports that betel nut contains a variety of chemical components,including alkaloids,polyphenols,flavonoids,terpenes,etc.,which has antioxidant,anti-inflammatory,antibacterial,anti-tumor,protection of gastrointestinal mucosa,expelling worms,anti-platelet,anti-atherosclerosis,improving osteoporosis,anti-depression and anti-fatigue,regulating endocrine function,regulating intraocular pressure,anti-viral and other effects.Some of these effects have a positive role in the prevention and treatment of related clinical diseases.However,it has certain toxicity to the reproductive system,urinary system,liver,heart,and oral mucosa.In order to fully develop and utilize betel nut,a review of its chemical components and pharmacological effects is presented,with the aim of providing references for the modernization research of betel nut and providing basis for its application in clinic.
Keywords：areca nutchemical compositionpharmacological effecttoxic effectclinical
Publication Date：2025-11-30
Online Publishing Date：2026-08-14(First online date of this platform, not the publication date of the document)
Pages：9( 2399-2407 )