Quality analysis of Reyihan granules
LIU De-yong
WANG Xin-chun
Payman HERMITY
HUANG Chuan-sheng
HE Cheng-hui
Abstract：Objective:To set up the quality standards of Reyihan granules.Methods:The identification items for Ocimi basilici Fructus,Roses rugosae Flos,Nardostachyos radlx Et Rhizoma,and Foeniculi fructus were established using TLC.The characteristic chromatogram was established,and the contents of gallic acid and rosmarinic acid in Reyihan granules were determined using HPLC.Results:The TLC identification method for Ocimi basilici Fructus,Roses rugosae Flos,Nardostachyos radlx Et Rhizoma,Foeniculi fructus had clear spots,with no interference from negative controls.There were 35 characteristic peaks in the HPLC characteristic chromatogram of Reyihan granules.Through comparison with reference standards,13 compounds were identified.Gallic acid showed a good linear relationship within the range of 1.3032～13.0320 μg·mL-1(r=0.9997),with an average recovery rate of 97.23%and an RSD of 1.20%(n=6).Rosmarinic acid showed a good linear relationship within the range of 2.462 4～24.624 0 μg·mL-1(r=0.999 3),with an average recovery rate of 102.79%and RSD of 1.10%(n=6).Conclusion:This method has strong specificity,good repeatability and stability,and can achieve quality control of Reyihan granules.
Keywords：Reyihan granulesTLCcharacteristic chromatogramHPLCquality standard
Publication Date：2025-09-15
Online Publishing Date：2026-08-14(First online date of this platform, not the publication date of the document)
Pages：7( 1865-1871 )