Development of the 14th national reference standard for histamine phosphate
ZHANG Yuan
GUO Long-jing
YANG Ze-an
TAN De-jiang
WU Yan-lin
Abstract：Objective:To establish the 14th batch of national reference standards for histamine phosphate.Methods:Histamine phosphate was identified using infrared spectroscopy and bioactivity assay.Its hygroscopicity,moisture content,and uniformity were also examined.Using the 13th batch of national reference standard for histamine phosphate as the standard,4 laboratories were selected to conduct collaborative calibration of the potency of the reference standard using the cat blood pressure method.Results:The final combined potency of this batch of standard products was determined to be 97.8%.Conclusion:This batch of reference materials can be used as the 14th batch of national reference materials for histamine phosphate,with a relative potency set at 100%,batch numbers 150510-202214.
Keywords：histamine phosphatenational reference standardstandard material determination valuedepressor substance test
Publication Date：2025-09-15
Online Publishing Date：2026-08-14(First online date of this platform, not the publication date of the document)
Pages：6( 1852-1857 )