Progress in the study of chemical composition and pharmacological effects of Imperatae rhizoma and its quality marker prediction
LI Shuai-yin
YANG Ping
XI Hui-rong
CHEN Ting
LI Xi-xiang
Abstract:Imperatae rhizoma is a traditional medicinal and edible homologous Chinese medicinal material,with a long history of application,rich chemical composition and a wide range of pharmacological effects.Its main components include triterpenes,phenylpropanoids,organic acids,flavonoids,steroids,volatile substances,polysaccharides and other classes of chemical compositions.These components are recognized for their diverse effects,including hemostatic properties,antitumor activity,enhancement of kidney function,anti-inflammatory effects,anthelmintic action,antimicrobial properties,antioxidant capabilities as well as hypoglycemic and hypotensive effects.By summarizing the chemical constituents and pharmacological effects of Imperatae rhizoma,the predictive analysis of its quality markers(Q-Marker)showed that chlorogenic acid,arundoin,cylindrene,imperanene,p-coumaric acid,luteolinidin chloride,bifendate,5-hydroxymethylfurfural,triterpene,and polysaccharides could be used as its potential Q-Marker.These Q-Markers can be used as reference for the improvement of the quality evaluation system of Imperatae rhizoma.
Keywords:Imperatae rhizomachemical compositionpharmacological effectsquality markersarundoinpolysaccharides
Publication Date:2025-07-15
Online Publishing Date:2026-08-14(First online date of this platform, not the publication date of the document)
Pages:11( 1406-1416 )
Chinese Journal of New Drugs

Chinese Journal of New Drugs

ISTICPKUCSCD
ISSN:1003-3734
Year, Vol.(Issue):2025,34(13)