Analysis of the status of vaccine clinical trials in Chinese pediatric population
WANG Ting-yu
LI Xin
DONG Ya-wen
SUN Yan-yan
Abstract：Objective:To provide reference for the development of vaccine clinical trials in Chinese pediatric population.Methods:Information related to vaccine clinical trials in Chinese pediatric population was collected from the website Chinadrugtrials.org.cn,which was statistically analyzed in quantity of registered trails in each year,trial stages,vaccines types,trial types,insurance,etc.Results:From September 6,2013 to December 31,2023,a total of 430 clinical trials involving pediatric population were registered on the website.Among these clinical trials,many trails were during phase Ⅲ.All vaccines used in the trials were preventive vaccines,and combined vaccines were the research focus.The homogenization of vaccine researches became a serious problem.The trials were mainly initiated by enterprises,among which rare trials started in three-tier medical institutions.Only 2 trials were classified as multi-regional clinical trial.120 trials were purchased insurance.Conclusion:Although vaccine clinical trials in Chinese pediatric population have developed steadily in recent years,but there is obvious gap in vaccine research between international standards and China,so it is necessary to accelerate the development of vaccine clinical trials in pediatric population.
Keywords：chinadrugtrials.org.cnpediatric populationvaccine clinical trialsstatus analysis
Publication Date：2025-05-30
Online Publishing Date：2026-08-14(First online date of this platform, not the publication date of the document)
Pages：5( 1096-1100 )