The urgency of constructing a method for evaluating the clinical efficacy of traditional Chinese medicine and a three-integrated review system:thoughts on the clinical study of Zhongfeng Xingnao oral prescription for the treatment of acute cerebral hemorrhage published in Lancet
XU Jia-xin
WANG Jian-xin
YU Zong-liang
GAO Rui
Abstract：With the development of research technology and the advancement of evidence-based medicine,a large number of high-level randomized controlled studies on the efficacy and safety of traditional Chinese medicine(TCM)have been conducted and published,laying a solid foundation for evidence-based research on TCM.Recently,Lancet published the main results of the CHAIN trial,a large-sample,multi-center,randomized con trolled study led by a research team from Fudan University and Guangdong Provincial Hospital of Traditional Chinese Medicine.Its negative findings have caused extensive discussion among researchers in TCM and related fields.This article provides some thoughts on the study and its implications for the approval of new traditional Chinese medicines.
Keywords：Zhongfeng Xingnao oral prescriptionacute cerebral hemorrhagerandomized controlled studytriple combination review systemevaluation of clinical efficacy of traditional Chinese medicine
Publication Date：2025-04-30
Online Publishing Date：2026-08-14(First online date of this platform, not the publication date of the document)
Pages：5( 785-789 )