Research progress of biomimetic carrier of cancer cell membrane in tumor therapy
SONG Xin
XU Bo-hua
WANG Shu-zhe
TAO Qiao-yu
FU Li-li
SUN Lu-yao
QIU Yun-liang
Abstract：Tumor therapy has always been the focus of study.Due to the variability of tumor cells,the complexity of the tumor microenvironment and other factors,the problems such as multidrug resistance of tumors,reduced drug delivery efficiency are obtained.In recent years,increasing attention has been paid to biomimetic vectors,in which cancer cell membrane(CCM)is a new type of nano-carrier with the characteristics of homologous targeting,immune escape and penetrating biological barrier.Using CCM as a bionic carrier to coat different types of nanoparticles(NPs)can achieve effective tumor targeting and advantages in tumor therapy.This review introduces the biomimetic vector of CCM,briefly describes the preparation process of NPs coated with CCM,summarizes the research of CCM in tumor drug delivery and tumor vaccine,and discusses the future development prospects of CCM.
Keywords：biomimetic carrierscancer cell membranesnanoparticlesdrug deliverytumor vaccine
Publication Date：2023-12-15
Online Publishing Date：2026-08-14(First online date of this platform, not the publication date of the document)
Pages：8( 2403-2410 )