Research progress in quantitative analysis methods of new immunosuppressants in human blood
YIN Hang
GENG Fang
LI Zhe
WANG Zheng
SHEN Su
YU Jun-xian
WANG Ru-long
Abstract：Immunosuppressive agents have been widely used in organ transplantation,autoimmune diseases and allergic reactions.With the development of science and technology,more new immunosuppressive agents have been put into clinical use.However,the adverse reactions have not been fully improved.It is still necessary to monitor the blood concentrations of the drugs.The pharmacokinetic and bioequivalence studies of related drugs also need development of quantitative analysis methods in human blood.Therefore,this article will make a review on the quantitative methods of several new clinical immunosuppressive agents in human blood such as mizoribine,leflunomide,fingolimod,ATG and traditional Chinese medicine immunosuppressant Tripterygium Wilfordii and Baishao preparation.
Keywords：new immunosuppressantblood concentrationquantitative methods
Publication Date：2017-01-01
Online Publishing Date：2026-08-14(First online date of this platform, not the publication date of the document)
Pages：7( 2681-2687 )