The application of circulating tumor DNA assay based on deep sequencing in cancer diagnosis and treatment
ZHOU Chun-lian
XU Wei-wen
Abstract：Circulating tumor DNA has evolved to be a promising noninvasive marker of tumor evaluation.Monitoring circulating tumor DNA with deep sequencing-based assays has lots of advantages and applications.The advantages include ultra-sensitivity and specificity,noninvasiveness and less heterogeneity.The applications include monitoring of tumor burden,monitoring of minimal residual disease and recurrence,personalized treatment and assessment of prognosis of tumor.In this article,we reviewed the clinical applications of deep sequencing-based circulating tumor DNA assay.
Keywords：deep sequencingcirculating tumor DNAtumor biomarkerstargeted therapyliquid biopsy
Publication Date：2017-01-01
Online Publishing Date：2026-08-14(First online date of this platform, not the publication date of the document)
Pages：5( 2401-2405 )