Research progress of the detection of fatty acids by liquid chromatography-mass spectrometry
ZHAO Mei-na
DUAN Jia-lin
MU Fei
LIN Rui
XI Miao-miao
Abstract：In recent years,high performance liquid chromatorgraphy-mass spectrometry (HPLC-MS) is widely used in biological (proteins,peptide,and nucleic acid),environmental protection and medical research.HPLC-MS has the feathers of HPLC-like high separation efficiency for complex samples,and instrument automatization;it also has the properties of MS-like good specificity,sensitivity,selectivity,fast analysis speed,and powerful structural determination (with relative molecular mass and structural information).With the development of modern high-tech,HPLC-MS will play a more important role in various testing fields in the future.Fatty acids (FA) are a series of organic compounds which consisted of three elements:carbon,hydrogen,and oxygen.With sufficient oxygen supply,FA could be oxidized into CO2 and H2O,and release a large amount of energy (one of the main sources of energy within the body).In this paper,we reviewed the applications of HPLC-MS technique in the detection of FA in different samples,and discussed the existing problems.In addiation,application prospect of HPLC-MS in the field of biochemistry was also discussed.
Keywords：HPLC-MSbiochemistryfatty acids
Publication Date：2017-01-01
Online Publishing Date：2026-08-14(First online date of this platform, not the publication date of the document)
Pages：7( 2278-2284 )