Advances in preparation of mesoporous silica nanoparticles and its use as different functional drug
YU Yue
TAO Chun
YANG Hai-yue
WANG Tian-yu
XUE Dan-ping
TIAN Xue-mei
ZHANG Mei-jing
FANG Sheng-nan
SONG Hong-tao
Abstract：In the past a few years,mesoporous silica nanoparticles (MSN) have attracted more and more attention for their application in drug delivery.The recent relative literature was used for reference to introduce the characteristics and preparation of M41S series MSN (synthesized by Mobil Corporation),the SBA series MSN (synthesized by Santa Barbara University),and hollow mesoporous silica nanoparticles.Examples were presented to introduce the use of MSN as immediate drug delivery carrier.The use of MSN as controlled drug delivery carrier (CDDC) was illustrated via pH-responsive CDDC,temperature-sensitive CDDC,and light-triggered CDDC.MSN showed great properties in immediate/sustained/controlled drug delivery system,in view of their unique mesoporous pore diameter,adjustable nano-channel,and surface easily to be modified.The selection of MSN as drug carrier has a broad application prospect.
Keywords：mesoporous silica nanoparticlesimmediate drug delivery carriersustained drug delivery carriercontrolled drug delivery carrier
Publication Date：2017-01-01
Online Publishing Date：2026-08-14(First online date of this platform, not the publication date of the document)
Pages：7( 1906-1912 )