Meta-analysis of efficacy and safety of rivaroxaban compared with dabigatran in patients undergoing catheter ablation for atrial fibrillation
ZHANG Chun-yan
REN Xiao-lei
FENG Wan-yu
Abstract：Objective:To evaluate the efficacy and safety of rivaroxaban and dabigatran in atrial fibrillation patients undergoing catheter ablation.Methods:Literature analysis based on evidence-based medicine was performed.Computer retrieval was conducted to search for random controlled trials,prospective studies and retrospective studies of rivaroxaban and dabigatran used in the periprocedural period of catheter ablation for atrial fibrillation.The quality of included studies was evaluated.Data were extracted into a specially designed extraction form.The Cochrane collaboration's RevMan5.3 software was used for data analysis.Results:The meta-analysis of nine included studies showed no significant difference between rivaroxaban and dabigatran in the efficacy and safety.Conclusion:Our study suggested that the patients treated with rivaroxaban during catheter ablation period had similar incidences of thromboembolic events and major hemorrhage compared with those treated with dabigatran to further validate this finding.
Keywords：rivaroxabandabigatrancatheter ablationatrial fibrillationefficacysafetyMeta-analysis
Publication Date：2017-01-01
Online Publishing Date：2026-08-14(First online date of this platform, not the publication date of the document)
Pages：5( 1418-1422 )