Adverse drug reactions induced by ticagrelor:an analysis of domestic and foreign literature
ZHANG Jian-hong
ZHU Li-qin
TIAN Dan-li
LIU Zi-yan
HUANG Hong-na
Abstract：Objective:To analyze the situation and clinical characteristics of adverse drug reactions (ADRs) induced by ticagrelor in order to provide references for rational drug use.Methods:CNKI,VIP and Pubmed databases were searched for ADRs induced by ticagrelor from January 2011 to July 2016.The collected case reports were further analyzed statistically.Results:Totally 25 patients were retrieved for analysis on ADRs induced by ticagrelor,among which there were 20 male patients accounting for 80.0％.Aged patients over 60 years-old showed a higher incidence (n =18,72％).ADRs of ticagrelor always occurred within three days after medication (n =16,64％).ADRs were chiefly mainfested as respiratory system disorders (n =9,36％) and cardiovascular system damage (n =5,20％).Conclusion:Clinicians should use ticagrelor reasonably and tighten monitoring on its use to reduce the incidences of ADRs.
Keywords：ticagreloradverse drug reaction (ADR)literature analysis
Publication Date：2017-01-01
Online Publishing Date：2026-08-14(First online date of this platform, not the publication date of the document)
Pages：4( 1335-1338 )