Impact of Yixinshu capsules on quality of life, anxiety and depression of coronary heart disease patients after PCI

GAO Jian-bu; LI Yu-dong; YANG Shou-zhong; WEN Gong-ling; CUI Shuang

Abstract：Objective:To investigate the quality of life of patients with anxiety and depression state after percutaneous coronary interventional (PCI) and the impact of Yixinshu capsules.Methods:A total of 1 367 patients with PCI operation were selected from Nanyang Central Hospital from January 2014 to August 2015.According to Self-Rating Depression Scale (SDS) and Self-Rating Anxiety Scale (SAS),anxiety were found in 287 patients,depression in 256 patients,and anxiety and depression in 183 cases.The patients with anxiety and depression were divided into the experimental and control groups.The control group received conventional treatment,and the experimental group received Yixinshu capsules three times a day in addition to the conventional treatment.The therapeutic effects of Yixinshu capsules on the quality of life and incidence of anxiety and depression and the adverse reactions were observed.Results:The baseline data,quality of life,HAMA score,and HRSP score before treatment had no significant difference between the two groups.After 1 month of therapy,the score of quality of life in the experimental group had significant (P ＜ 0.05) or extremely significant (P ＜ 0.01) difference compared with the control group;the HAMA scores and HRSP score were significantly lower than the control group (P ＜ 0.05).After 3 months of treatment,the scores of quality of life,HAMA scores,and HRSP scores had extremely significant difference between the two groups (P ＜ 0.01).Conclusion:A high incidence of anxiety and depression exists after PCI.Yixinshu capsules can relieve anxiety and depression and improve the quality of life of the patients.