Efficacy of flurbiprofen axetil combined with fentanyl for postoperative analgesia in patients undergoing laparoscopic surgery
WANG Qian
WANG Tian-long
WEI Li-min
Abstract：0bjective: To evaluate the efficacy of flurbiprofen axetil combined with fentanyl for postoperative analgesia in patients undergoing laparoscopic surgery. Methods: Patients (ASA I-Ⅱ)undergoing laparo-scopic surgery(n=54)were randomly divided into control(n=28)and analgesia(n=26)groups. The analgesia group received patient-controlled intravenous analgesia(PCIA)with flurbiprofen axetil and fentanyl, namely flurbi-profen axetil 100 mg+fentanyl0.5 mg + ondansetron 8mg that was diluted with 80 mL saline. PCIA was performed as following: a bolus of 0.5 mL,lockout time of 15 min, and background dose of 2 mL-h~(-1).Postoperative pain was assessed by visual analogue scale(VAS)at 4,8,24 and 48 h after the surgery. Side effects and sleep quality were also recorded. Results: The VAS was significantly lower in analgesia group than in control group. Sleep quality was better in the analgesia group. There was no difference of side effects in the two groups. Conclusion: Co-administration of flurbiprofen axetil and fentanyl by PCIA is an effective method for postoperative analgesia in patients under-going laparoscopic surgery.
Keywords：flurbiprofen axetilfentanylpostoperative analgesialaparoscopesurgery
Publication Date：2010-01-01
Online Publishing Date：2026-08-14(First online date of this platform, not the publication date of the document)
Pages：3( 42-44 )