Advance in research on periodontal sustained-release local drug delivery systems
LIU Qing-xiao
YANG Mei-yan
GAO Chun-sheng
Abstract：Periodontal disease is a kind of local inflammatory and destructive diseases,and it is one of the most common human oral diseases. Compared with systemic administration,periodontal sustained-release local drug delivery systems can not only achieve high drug concentration and slow drug release in periodontal pocket,but also minimize side effects and bacterial resistance to drugs caused by systemic administration. Therefore,periodontal sus-tained - release local drug delivery systems have become the focus of the study on periodontal disease therapy at home and abroad. At present,the periodontal sustained-release local drug delivery systems include fiber,film,micro-spheres,gels,stylus and bucco-adhesive tablets. In this article,we reviewed the advance in research on periodontal sustained-release local drug delivery systems.
Keywords：periodontal diseaseslocal drug deliverysustained-release gelsdoxycycline hydrochloride
Publication Date：2009-01-01
Online Publishing Date：2026-08-14(First online date of this platform, not the publication date of the document)
Pages：5( 2228-2232 )