Analgesic efficacy of oxycodone-acetaminophen tablets in the treatment of pain
WANG Suo-liang
SHEN Xiao-dong
WANG Hui
HOU Hai-tao
Abstract：Objective:To observe the analgesic efficacy and side effects of oxycodone-acetaminophen tab-lets for the painful diseases and the cancer pain at middle and advanced stages. Methods: Out-patients with non-cancer pain (n = 50, painful disease) and patients with cancer pain (n = 30) were enrolled, and treated with oxyc-odone-acetaminophen 1～2 tablets, bid or tid. The analgesic effects and side effects were respectively observed 5 days after treatment in painful disease group, and 7 days after treatment cancer pain group. Results:The analgesic efficacies were satisfactory in both groups; the total pain relief rate was 100%. The complete relief rate was 87.3% in painful disease group and 70% in cancer pain group. The side effects included dizziness, lethargy, nausea, vomi-ting, and constipation. No obvious respiratory depression and psychological dependence were observed. Conclusion: oxycodone-acetaminophen has definite analgesic effect and slight adverse reactions in the treatment of painful disea-ses and cancer pain.
Keywords：oxycodone-acetaminophenanalgesic efficacynon-cancer paincancer pain
Publication Date：2009-01-01
Online Publishing Date：2026-08-14(First online date of this platform, not the publication date of the document)
Pages：3( 2135-2137 )