A new nonpeptidic protease inhibitor——darunavir
ZHENG Yu-jing
ZHANG Ya-tong
LIANG Xin
FU De-xing
Abstract：The aim is to introduce the pharmacology of darunavir. The pharmacokinetic parameters, clini-cal application and evaluation were reviewed from the newest published documents. As a new nonpeptidic protease inhibitor, darunavir combined with ritonavir(DRV/R) is approved for the treatment of antiretroviral therapy-experi-enced patients and was proved with good clinical efficacy and tolerance.
Keywords：darunavirHIVprotease inhibitorpharmacologyclinical evaluation
Publication Date：2009-01-01
Online Publishing Date：2026-08-14(First online date of this platform, not the publication date of the document)
Pages：4( 2131-2134 )