A selective cooxygenase-2 inhibitor for injection: parecoxib sodium
CUI Xiang-li
ZHAO Zhi-gang
CHEN Li
LI Ming
Abstract：parecoxib sodium, the first injection preparation of selective cyclooxygenase-2 inhibitors, is used as an analgesic for acute postoperative pain. Its efficacy has been proved in the stomatologic, gynecologic, or orthopedic surgery. Intravenous paricoxib 40 rag, twice a day, can also reduce the morphine consumption and im-prove postoperative analgesia. In this review, we summarized the pharmacological mechanism, clinical research and safety of parecoxib.
Keywords：parecoxib sodiumcyclooxygenase-2 (COX-2)non-steroidal anti-inflammatory drugs(NSAIDs)analgesia
Publication Date：2009-01-01
Online Publishing Date：2026-08-14(First online date of this platform, not the publication date of the document)
Pages：4( 1283-1286 )