Study on antiinflammatory effect of meloxicam in animals
XU Hui
YAO Quan-sheng
ZHOU Guo-lin
Abstract：Objective:To study the antiinflammatory effect of meloxicam in animals.Methods:3 kinds of animal model for experimental inflammation,including carrageenin-induced paw edema,cotton-ball granuloma and adjuvant induced arthritis,were adopted to validate the antiinflammable effect of meloxicam.Results:Meloxicam showed a marked inhibitory effect on carrageenin-induced paw edema and cotton-ball granuloma in rats,the inhibitory rate of meloxicam at the dose of 1.0,3.0mg*kg-1 in granuloma model were 36.59% and 52.34% respectively.In addition,meloxicam also showed a significant therapeutic effect on adjuvant induced arthritis in rats and improved the pathological changes of the induced athritis.Conclusion:Meloxicam shows significant antiinflammatory effects on animal models mentioned above.
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Publication Date：2001-01-01
Online Publishing Date：2026-08-14(First online date of this platform, not the publication date of the document)
Pages：3( 345-347 )