A randomized controlled multicenter clinical trial on theefficacy and safety of recombinant interferon α-2a(yeast) injection in treatment of herpes zoster
JIN Hong-zhong
WANG Jia-bi
FANG Li
FU Wen-wen
XU Shi-zheng
WANG Xiu-li
ZHU Wen-yuan
FAN Wei-xin
Abstract：Objective:To study the efficacy and safety of recombinant interferon α-2a(yeast) injection in treatment of herpes zoster.Methods:In the randomized,controlled and multicenter study,recombinant interferon α-2a (yeast) was used in the active group and interferon α-2a(E.Coli) in the controlled group.In 210 patients recruited,206 completed the trial.Among them 102 were in the active group and 104 in the controlled group.Results:Results obtained showed that there were no statistical significant differences among groups in duration of new blister appearance and blister disappearence;duration of starting crustation,acute pain resolving, and postherpetic neuralgiare resolving.There was statistical significant difference among groups in duration of complete crustation.For incidence of side effects (13.73% for active and 21.15% for controlled group),there were no statistical significant difference between groups.Conclusion:Recombinant interferon α-2a (yeast) injection is an effective and safe agent for treatment of herpes zoster.
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Publication Date：2001-01-01
Online Publishing Date：2026-08-14(First online date of this platform, not the publication date of the document)
Pages：3( 277-279 )