The efficacy and safety of trimebutine maleate in the treatment of irritable bowel syndrome
WANG Hui-ji
YU Zhong-lin
ZHOU Li-ya
LIN San-ren
LIU Xing-guang
Abstract：Objective:To validate the clinical safety and effic acy of trimebutine maleate(Cerekinon) in treatment of irritable bowel syndrome(I BS).Methods:64 patients with IBS were recruited into the study.Aft er 2 weeks placebo treatment 15 patients were excluded from the study due to sym ptoms relief.The balance of 49 patients were treated with Cerekinon 200mg,po,tid for 2 weeks.Results:After 2 weeks treatment,the following result s were obtained:91.8% reduction in abdominal pain;89.8% reduction in abnormal de fecation;86.6% reduction in diarrhoea;81.8% reduction in constipation;and a tota l effective rate 81.6%.No side effect was observed.Conclusion:Cere kinon is an effective agent for treatment of IBS.
Machine-generated Keywords：
Publication Date：2001-01-01
Online Publishing Date：2026-08-14(First online date of this platform, not the publication date of the document)
Pages：3( 207-209 )