The efficacy of lamivudine in prevention and treatment of the replication and reinfection of hepatitis B virus in patients with nephratic syndrome
WEI Feng
Abstract：Objective:To observe the feasibility of lamivudine in pr eventing and treating the replication and reinfection of hepatitis B virus in pa tients with nephratic syndrome treated with prednisone.Methods:5 patie nts with nephratic syndrome and positive marker of hepatitis B virus,were treate d with oral prednisone or combination therapy of mycophenolate mofetil and lamiv udine.The pre- and post-treatment changes in marker of hepatitis B virus and i n liver functions were observed.Results:After 3 months treatment,HBeAg turned to negative in 1 patient and ALT and AST turned to normal in 1 patient. After 6 months treatment,HBeAg turned to negative in 1 patient and no exacebatio n in marker of hepatitis B virus and liver functions was observed in patients.Conclusion:Lamivudine is effective in preventing and treating replicatio n and reinfection of hepatitis B virus in patients with nephratic syndrome treat ed with prednisone.
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Publication Date：2001-01-01
Online Publishing Date：2026-08-14(First online date of this platform, not the publication date of the document)
Pages：2( 127-128 )