Study of the effect of meglumine cyclic adenyl ate on platelet function of rats
LIU Gui-lan
XU Zhi-hua
Abstract：Objectives:As stated in the title.Methods:50 rats were randomly and equally divided to receive tail venous injection o f saline for 3d;dipyridamole in regimen of 5 mg/kg×3d;MCA in 3 different regime n of 10 mg/kg×3d;20 mg/kg×3 d;and 40 mg/kg×3 d.The platelet aggregation was d etermined using ADP and collagen as inducing agents.The tail artery blooding tim e was also determined using another 20 rats receiving 10 mg/kg×3d given by peri toneal injection.Results:The platelet aggregation induced by ADP a nd collagen can be inhibited by MCA and the rats'tail artery blooding time can b e prolonged by it.Conclusions:The platelet function of rats can be inhibited by MCA.
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Publication Date：2001-01-01
Online Publishing Date：2026-08-14(First online date of this platform, not the publication date of the document)
Pages：3( 34-36 )