The applications of positron emission tomography(PET)in drug research and development
ZHONG Jian-guo
XIA Zhen-min
WANG Si-li
Abstract：The action of PET,a quantitative and multidimensional ph otograhic technique,is realized by detecting some pairs of gamma ray which are o pposite in direction but with equal energy of 511 keV photron,produced in proces s of annihilating positrons emitted from ultrashort radionuclides and electron f rom media.It is mainly used in studying the biochemical reaction accompanying th e process for realization of the physiological function of main organs or tissue s in living body.It can also be directly used in studying the bilgogical behavio r,efficacy,and toxicity of drugs in vivo .Therefore,PET has a broad prospect in drug research.In this paper,the instrument and mechanism of PET,radiolabeled compounds for PET studies,and its applications in drug research and its limitat ion were reviewed.
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Publication Date：2001-01-01
Online Publishing Date：2026-08-14(First online date of this platform, not the publication date of the document)
Pages：5( 6-10 )