Short-and long-term outcomes of the modified island technique treating type A aortic dissection patients in different age
ZHANG Xiao-yang
CHEN Su-wei
JIA Bo
LI Cheng-nan
QIAO Zhi-yu
GE Yi-peng
HU Hai-ou
ZHU Jun-ming
Abstract：Objective To retrospectively analyze the differences in the short-and long-term outcomes of modified island technique for treating type A aortic dissection(TAAD)across different age groups.Methods From January 2018 to July 2022,278 TAAD patients who underwent total arch replacement with modified island technique at Beijing Anzhen Hospital.They were divided into three age groups:the youth(＜45 years),the middle-aged(45-59 years)and the elderly(≥60 years).The in-hospital mortality,incidence of major adverse events(MAEs)and 5-year overall survival rates were compared among the groups.Results The elderly group exhibited significantly higher in-hospital mortality(25.00％vs.5.56％,P=0.001)and MAEs incidence(39.58％vs.14.81％,P=0.002)compared to the youth group.Compared to middle-aged group,elderly age was identified as an independent risk factor for in-hospital death[OR 4.04(1.11-14.70),P=0.034].Restricted cubic spline analysis revealed a significant dose-response relationship between age and in-hospital death(P for overall=0.002).The overall survival and freedom from reintervention rates at 5-year were 97.08％and 92.58％,respectively,with no intergroup differences(P＞0.05).Conclusion The modified island technique can be used for TAAD patients across multiple age groups.In elderly patients,the long-term outcomes is similar to that of young and middle-aged patients,but perioperative risks need to be critically evaluated.
Keywords：Stanford type A aortic dissectionAgeThe modified island technique
Publication Date：2025-04-20
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 348-353 )