Association between triglyceride-glucose index and arteriosclerosis in occupational population
WANG Xin
ZHOU Hao-qi
HU Zhen
ZHANG De-di
SHAN Wen-ping
SHAO Min
ZHANG Chuan-xi
YU Xue
ZHANG Chen-da
TIAN Yi-xin
CHANG Chen-ye
TIAN Ye
NIE Yu-xuan
WANG Zeng-wu
Abstract：Objective To investigate the relationship between triglyceride-glucose index and arteriosclerosis among the occupational population.Method Based on the"Evaluation of Cardiovascular Disease Risk Intervention Effect in Occupational Population Based on Mobile Health Technology"project,20 workplaces across the country were selected for the study.The basic information,physical examinations,and laboratory tests of the occupational population were collected.The triglyceride-glucose index was calculated as:Ln[TG(mg/dl)x FPG(mg/dl)/2].Logistic regression and restricted cubic splines were used to explore the relationship between triglyceride-glucose index and the risk of arteriosclerosis.Results A total of 2549 subjects were included.The average age was(44.3±10.1)years,with a male proportion of 79.5％.Logistic regression results indicated that after adjusting for related influencing factors,there was a positive correlation between triglyceride-glucose index and arteriosclerosis,with an odds ratio of 1.33(95％CI 1.17-1.51).The restricted cubic splines results showed a linear relationship between insulin resistance and arteriosclerosis in the overall population(P-Nonlinear=0.0836).Subgroup analysis revealed a linear relationship between insulin resistance and arteriosclerosis in the non-hypertensive population(P-Nonlinear=0.1089,OR=1.42,95％CI 1.12-1.80),whereas a nonlinear relationship was observed in the hypertensive population(P-Nonlinear=0.0053,OR=1.21,95％CI 0.98-1.51).Conclusion Among the occupational population,there is a positive correlation between triglyceride-glucose index and the risk of arteriosclerosis.
Keywords：Triglyceride-glucose indexOccupational populationArteriosclerosis
Publication Date：2024-11-10
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 1007-1012 )