Characteristics and in-hospital outcomes of non-ST-segment elevation myocardial infarction patients without standard modifiable cardiovascular risk factors
GUO Wei-hong
YIN Chun-lin
XIA Jing-gang
Abstract：Objective To compare the differences in characteristics and in-hospital outcomes between the non-ST-segment elevation myocardial infarction(NSTEMI)patients with and without standard modifiable cardiovascular risk factors(SMuRF)and explore the accounting factors to explain these differences.Methods 1211 patients with NSTEMI admitted to Xuanwu Hospital of Capital Medical University from January 2017 to December 2022 were included.SMuRF refers to any of the following risk factors:hypertension,diabetes,hyperlipidemia and smoking.The patients without SMuRF were also called"SMuRF-less"patients.Logistic regression models were used to compare the in-hospital outcomes between the patients with and without SMuRF.Results Among the patients(median age 64 years,24.5％women),7.3％were SMuRF-less.Compared with the patients with SMuRF,the SMURF-less group had a lower body mass index,less history of coronary heart disease and a higher proportion of left main lesions.There were no differences in the clinical conditions,the use of reperfusion and the rate of major adverse cardiovascular events(28.4％vs.33.8％,P=0.299)between the two groups.After multivariable adjustment,the risk of major adverse cardiovascular events between the 2 groups remained similar(OR=0.83,95％CI 0.43～1.62).Conclusion About one in ten patients with NSTEMI have no SMuRF,who have a higher proportion of left main lesions.There is no differences in treatment and in-hospital outcomes between the SMuRF and SMuRF-less patient.Whether there are differences in the etiology and pathophysiology remains to be determined.
Keywords：Myocardial infarctionStandard modifiable cardiovascular risk factorPatient characteristicsIn-hospital outcomeAtherosclerosis
Publication Date：2024-10-10
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 901-905 )